Orbital Myositis and Primary Sjögren Syndrome
Bibliographic record
Abstract
To the Editor: In this report, we describe a new systemic manifestation associated with primary Sjögren syndrome (pSS): orbital myositis (OM). Considered a systemic disorder, pSS is primarily characterized by lymphocytic infiltration of exocrine glands, resulting in functional impairment of salivary and lacrymal glands. The inflammatory process, however, extends beyond the exocrine glands and can potentially affect any organ. A 40-year-old white man with pSS was admitted with diplopia. Since 2002, his disease manifested with sicca syndrome, polyarthralgia, antinuclear antibodies, and anti-SSA and -SSB antibodies, and lymphocytic sialadenitis (focus score of 1) associated with Hashimoto thyroiditis. He previously developed 2 neurological complications: aseptic meningoradiculitis following treatment with infliximab in 2002 (in the Trial of Remicade in Primary Sjögren’s Syndrome randomized clinical trial)1, and bilateral idiopathic sudden … Address correspondence to Dr. X. Mariette, Hôpitaux Universitaires Paris-Sud, Assistance Publique des Hôpitaux de Paris, Hôpital Bicêtre, Service de Rhumatologie, 78 rue du Général Leclerc, Le Kremlin Bicêtre 94275, France. E-mail: xavier.mariette{at}bct.aphp.fr
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".