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Record W1843996120 · doi:10.2450/2010.011s

Towards targeting platelet storage lesion-related signaling pathways.

2010· article· en· W1843996120 on OpenAlexaff
Peter Schubert, Dana V. Devine

Bibliographic record

VenuePubMed · 2010
Typearticle
Languageen
FieldMedicine
TopicBlood transfusion and management
Canadian institutionsCanadian Blood ServicesUniversity of British Columbia
Fundersnot available
KeywordsPlateletMedicinePlatelet transfusionLesionBlood productBlood bankThrombosisSurgeryIntensive care medicineImmunologyMedical emergency

Abstract

fetched live from OpenAlex

Blood platelets play a pivotal role in thrombosis and haemostasis. Platelet transfusions are life-saving medical procedures for patients undergoing major surgery or suffering from diseases such as cancer or thrombocytopenia. Research efforts in transfusion science are applied to the banking of platelets in areas ranging from donor genotyping to the improvement of the blood component processing procedure and determination of product quality. After production, platelet concentrates are stored at room temperature (20–24 °C) with agitation for only 4–7 days. This shelf-life restriction is imposed by health regulatory authorities in order to ensure safety and quality of the blood product owing to the risk of bacterial growth and the loss of platelet viability during storage commonly referred to as the “platelet storage lesion” (PSL).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: none
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.225
Teacher spread0.200 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations30
Published2010
Admission routes1
Has abstractyes

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