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Record W1855449067 · doi:10.1016/j.clim.2015.10.005

Lack of IL7Rα expression in T cells is a hallmark of T-cell immunodeficiency in Schimke immuno-osseous dysplasia (SIOD)

2015· article· en· W1855449067 on OpenAlex
Mrinmoy Sanyal, Marie Morimoto, Alireza Baradaran‐Heravi, Kunho Choi, Neeraja Kambham, Kent P. Jensen, Suparna Dutt, Kira Y. Dionis-Petersen, Lan Xiang Liu, Katie Felix, Christy Mayfield, Benjamin Dekel, Arend Bökenkamp, Helen Fryssira, Encarna Guillén‐Navarro, Giuliana Lama, Milena Brugnara, Thomas Lücke, Ann Haskins Olney, Tracy E. Hunley, Ayşe Polat, Uluç Yiş, Radovan Bogdanović, Katarina Mitrović, Susan A. Berry, Lydia Najera, Behzad Najafian, Mattia Gentile, C. Nur Semerci, Michel Tsimaratos, David B. Lewis, Cornelius F. Boerkoel

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueClinical Immunology · 2015
Typearticle
Languageen
FieldImmunology and Microbiology
TopicImmunodeficiency and Autoimmune Disorders
Canadian institutionsChild and Family Research InstituteUniversity of British Columbia
Fundersnot available
KeywordsInterleukin-7 receptorImmunodeficiencyMedicineDysplasiaImmunologyCancer researchBiologyT cellInternal medicineImmune systemIL-2 receptor

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.003
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.095
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0030.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0020.000
Bibliometrics0.0010.001
Science and technology studies0.0000.002
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0010.002
Insufficient payload (model declined to judge)0.0000.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.333
Teacher spread0.277 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it