Clinical evaluation of long range adaptive control for mean arterial blood pressure regulation
Why this work is in the frame
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Bibliographic record
Abstract
A computerized drug delivery system has been designed for automatic regulation of mean arterial pressure (MAP) of human patients by infusion of a vasodilator (sodium nitroprusside). This control system employs a predictive control algorithm with a combination of finite-horizon and an infinite horizon optimization terms. The control algorithm operates in an adaptive mode by coupling it to a recursive, control-relevant identification algorithm for long-range predictive control. The proposed system was used to perform closed-loop regulation of MAP of two patients, in an intra-operative environment, in the cardiac unit of the University of Alberta Hospital. The MAP trajectories show that the patient's MAP stayed within /spl plusmn/10 mmHg of the setpoint for more than 70% of the time even in the presence of significant natural disturbances.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it