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THE REPORTING OF IRB REVIEW IN JOURNAL ARTICLES PRESENTING HIV RESEARCH CONDUCTED IN THE DEVELOPING WORLD

2011· article· en· W1878606909 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueDeveloping World Bioethics · 2011
Typearticle
Languageen
FieldMedicine
TopicEthics in Clinical Research
Canadian institutionsColumbia College
FundersU.S. National Library of MedicineNational Human Genome Research InstituteNational Institute of Mental HealthNational Heart, Lung, and Blood Institute
KeywordsHuman immunodeficiency virus (HIV)MedicineOriginal researchInstitutional review boardMedical journalDeveloping countryFamily medicineResearch ethicsPsychosocialInclusion (mineral)Ethics committeePolitical scienceLibrary scienceSocial scienceSociologyPsychiatryPublic administrationEconomic growth

Abstract

fetched live from OpenAlex

OBJECTIVES: We investigated how often journal articles reporting on human HIV research in four developing world countries mention any institutional review boards (IRBs) or research ethics committees (RECs), and what factors are involved. METHODS: We examined all such articles published in 2007 from India, Nigeria, Thailand and Uganda, and coded these for several ethical and other characteristics. RESULTS: Of 221 articles meeting inclusion criteria, 32.1% did not mention IRB approval. Mention of IRB approval was associated with: biomedical (versus psychosocial) research (P=0.001), more sponsor-country authors (P=0.003), sponsor-country corresponding author (P=0.047), mention of funding (P<0.001), particular host-country involved (P=0.002), journals having sponsor-country editors (P<0.001), and journal stated compliance with International Committee of Medical Journal Editors (ICMJE) guidelines (P=0.003). Logistic regression identified 3 significant factors: mention of funding, journal having sponsor-country editors and research being biomedical. CONCLUSIONS: One-third of articles still do not mention IRB approval. Mention varied by country, and was associated with biomedical research, and more sponsor country involvement. Recently, some journals have required mention of IRB approval, but allow authors to do so in cover letters to editors, not in the article itself. Instead, these data suggest, journals should require that articles document adherence to ethical standards.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.143
metaresearch head score (Gemma)0.208
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMetaresearch, Research integrity
Consensus categoriesMetaresearch
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.543
Threshold uncertainty score0.998

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.1430.208
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.006
Science and technology studies0.0010.002
Scholarly communication0.0000.000
Open science0.0010.001
Research integrity0.0000.011
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.892
GPT teacher head0.642
Teacher spread0.249 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it