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Record W1903762917 · doi:10.1002/047167849x.bio059

Toxicity and Safety of Fats and Oils

2005· other· en· W1903762917 on OpenAlexaff
David D. Kitts

Bibliographic record

VenueBailey's Industrial Oil and Fat Products · 2005
Typeother
Languageen
FieldMedicine
TopicAntioxidant Activity and Oxidative Stress
Canadian institutionsUniversity of British Columbia
Fundersnot available
KeywordsToxicityChemistryFood scienceXenobioticToxicologyBiochemistryBiologyOrganic chemistry

Abstract

fetched live from OpenAlex

Abstract The past two decades has produced an ever increasing awareness of the role of dietary fat in the etiology of different chronic diseases (e.g. diabetes, coronary heart disease and cancer). In addition, advances in food technology methods for preserving and processing food lipids for retained nutritional and sensory appeal has coincided with increased awareness concerning the safety of dietary fats and oil sources, as they relate to both the visible and non‐visible components of the total crude lipid fraction. Increased calorie consumed from fat sources not only provides consumer exposure to natural fat and oil components (e.g. fatty acids, sterols etc.), but also derived products of oxidation and hydrogenation and the presence of natural, environmental (pollutants) or intentional (e.g. additives) xenobiotics which co‐exist, or accumulate, in the crude lipid fraction. Thus, understanding the safety of dietary fats and oils requires not only an awareness of the elements of lipid chemistry of soluble constituents in the lipid phase, but also the associated reaction conditions that may convert them to toxic products. Moreover, by predicting a risk from the combined relative toxicity and the level of exposure to the organism will enable assessment of a hazard to exposure to these chemicals. In this chapter, a number of reactive and labile fat soluble constituents are assessed for safety and potential toxicity in regard to both initiating and propagating the cascade of events that may lead to a toxic end‐point measure. Endogenous (e.g. co‐oxidation reactions) as well as exposure to exogenous (e.g. photoxidation or presence of man made pollutants) xenobiotics are analyzed in respect to the potential for inducing adverse health effects.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.005
Threshold uncertainty score0.015

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0010.000
Open science0.0000.000
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.263
Teacher spread0.227 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations13
Published2005
Admission routes1
Has abstractyes

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