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Record W1919309518 · doi:10.1186/ar1394

Differential induction of IL-1β and tumor necrosis factor by CD40 ligand or cellular contact with stimulated T cells depends on the degree of maturity of human monocytes

2004· article· en· W1919309518 on OpenAlexfundno aff
Danielle Burger, Nicolas Molnarfi, Lyssia Gruaz, J M Dayer

Bibliographic record

VenueArthritis Research · 2004
Typearticle
Languageen
FieldImmunology and Microbiology
TopicImmune Response and Inflammation
Canadian institutionsnot available
FundersCanadian Arthritis NetworkSchool of Medicine, University of California, San DiegoMenzies Institute for Medical ResearchNational Cancer InstituteArthritis SocietyUniversity of North Carolina at Chapel HillGenentechNational Institutes of HealthBiogenLupus Research InstitutePfizerNatural Sciences and Engineering Research Council of CanadaDutch Arthritis AssociationOesterreichische NationalbankDeutsche ForschungsgemeinschaftNuffield FoundationPhysiotherapy Foundation of CanadaCanadian Institutes of Health ResearchNational Institute of Arthritis and Musculoskeletal and Skin DiseasesLupus Research AllianceWellcome TrustNewcastle UniversityNational Institute of Allergy and Infectious DiseasesHoward Hughes Medical InstituteAustrian Science FundArthritis Foundation
KeywordsCD40Tumor necrosis factor alphaMonocyteCytokineCell biologyMacrophageChemistryMembraneBiologyMolecular biologyImmunologyBiochemistryIn vitroCytotoxic T cell

Abstract

fetched live from OpenAlex

One of the world's leading journals in the field of rheumatology, Arthritis Research & Therapy covers a broad range of autoimmune rheumatic and musculoskeletal diseases, and focuses on the translation of the latest knowledge into improving clinical care. Edited by renowned scholars, this open access journal publishes original translational laboratory and clinical research, as well as reviews, commentaries and reports. Highly recommended by contributing authors, it is widely considered to be essential reading for researchers, clinicians and students of rheumatology. Founding Editors Peter E. Lipsky, MD, Independent Rheumatologist, Charlottesville, Virginia, USA Emeritus Professor Sir Ravinder N. Maini, FRCP, FRCPE, FMedSci, Imperial College London, London, United Kingdom

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.012
Threshold uncertainty score0.332

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.290
Teacher spread0.234 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2004
Admission routes1
Has abstractyes

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