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Record W1926408434 · doi:10.3899/jrheum.150331

Defining Remission in Psoriatic Arthritis: Are We Getting Closer?

2015· letter· en· W1926408434 on OpenAlexvenueno aff
Enrique R. Soriano

Bibliographic record

VenueThe Journal of Rheumatology · 2015
Typeletter
Languageen
FieldMedicine
TopicSpondyloarthritis Studies and Treatments
Canadian institutionsnot available
Fundersnot available
KeywordsDactylitisMedicineEnthesitisPsoriatic arthritisRheumatoid arthritisPsoriasisInternal medicineRheumatologyDiseaseDermatologyPhysical therapy

Abstract

fetched live from OpenAlex

New paradigms in the management of psoriatic arthritis (PsA) are gaining great acceptance in the rheumatology community, including early treatment1, remission as a treatment objective2, assessment of all domains involved3, and frequent measuring of disease activity and adjusting therapy accordingly (treat to target)4. To achieve these goals, we need effective therapies. The introduction of biologic therapies, mainly tumor necrosis factor inhibitors (TNFi), has greatly improved our ability to treat the various manifestations of PsA. These various manifestations include peripheral and axial joint, skin, and nail involvement; enthesitis and dactylitis being among the more frequent ones. It is important to gather data for all these clinical features to assess disease activity. Remission criteria and activity indexes borrowed from rheumatoid arthritis (RA) have been used in PsA, but they clearly are unable to include all PsA manifestations2,5,6. Composite measures combine several dimensions of disease status, often by combining these different domains into a single score. Such indices seem to be more efficient than unidimensional instruments2,5,6. Composite measures, however, give rise to some concerns because a single measure that encompasses diverse domains might lose the ability to differentiate between activity in individual domains. At the OMERACT meeting (Outcome … Address correspondence to Dr. E.R. Soriano, Hospital Italiano de Buenos Aires, Sección Reumatología, Servicio de Clínica Médica, Gascon 450, Buenos Aires 1181, Argentina. E-mail: enrique.soriano{at}hospitalitaliano.org.ar

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.038
metaresearch head score (Gemma)0.079
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.038
Threshold uncertainty score0.199

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0380.079
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0060.001
Bibliometrics0.0030.004
Science and technology studies0.0030.007
Scholarly communication0.0090.022
Open science0.0030.005
Research integrity0.0080.019
Insufficient payload (model declined to judge)0.0060.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.024
GPT teacher head0.281
Teacher spread0.258 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2015
Admission routes1
Has abstractyes

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