Factors that predict length of home oxygen supplement in children with chronic lung disease of prematurity (CLD)
Bibliographic record
Abstract
Introduction:CLD is the most common cause of chronic lung disease in preterm infants, requiring oxygen supplement at home. Risk factors are described, factors that contribute or prolong oxygen supplement in CLD are not known Objectives:to identify antenatal, neonatal and postnatal factors predicting duration of home oxygen Methods:A retrospective study of infants born at ≤ 32 weeks GA, requiring oxygen supplement at 36 weeks postmenstrual age, discharged on home oxygen supplement (Jan, 2003–June, 2012). Children with significant co-morbidities were excluded. Demographic, antenatal, neonatal and postnatal data were extracted from computerized databases Results:141 subjects (51.8% male) with mean duration of oxygen use 202 days (SD ± 218 days). Mean adjusted age at discontinuation of oxygen supplement 31 weeks. Duration of oxygen supplement was strongly correlated with poor weight gain (r = 0.61, P<0.001) and longer total duration of hospitalization (r=.397, p<.001), longer mechanical ventilation (r=.358, p=.001), no antenatal corticosteroids (r= -.203, p=.016), higher CRIB II score (r=.219, p=.009), longer use of inhaled corticosteroids (r=.270, p=.001) and diuretics (r=.240, p=.005). The overall Poisson regression model was significant (chi square (3)=3425.25, p<.001). Both no antenatal corticosteroids (p=.005), having a higher CRIB II score (p=.007), and longer inhaled corticosteroid (p<.001) are predictive of a longer duration on oxygen supplement Conclusion:Children with CLD who did not receive antenatal corticosteroids, have higher CRIB II score and/or require longer duration of inhaled corticosteroids therapy will require longer duration of home oxygen supplement.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.003 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".