Bibliographic record
Abstract
[61717-82-6] C7H5IO4 (MW 280.01) InChI = 1S/C7H5IO4/c9-7-5-3-1-2-4-6(5)8(10,11)12-7/h1-4,10H InChIKey = MEOMMSSYMAPFRJ-UHFFFAOYSA-N (oxidizing agent, single-electron-transfer reagent)1 Alternate Name: o-iodoxybenzoic acid; 1-hydroxy-1,2-benziodoxol-3(1H)-one-1-oxide, IBX. Physical Data: mp 232–233 °C. Solubility: soluble in DMSO, DMSO/THF mixtures; insoluble in H2O and most organic solvents. Analysis of Reagent Purity: 1H-NMR (DMSO-d6) δ 8.15 (d, 1H), 8.01 (d, 1H), 7.98 (t, 1H), 7.84 (t, 1H). 13C-NMR (DMSO-d6) δ167.49, 146.59, 133.39, 132.97, 131.36, 130.10, 124.99.2 Preparative Methods: not commercially available. IBX was first synthesized in 1893,2 and is the penultimate precursor of the Dess-Martin periodinane reagent.3, 4 IBX is prepared by the slow addition (0.5 h) of potassium bromate (76.0 g, 0.45 mol) to a rapidly stirred sulfuric acid mixture (0.73 M, 730 mL) containing 2-iodobenzoic acid (85.2 g, 0.34 mol). The reaction temperature is maintained below 55 °C until addition is complete. The reaction mixture is heated to 65 °C for 3.6 h. The flask is cooled to 0 °C, and the solid is filtered and washed with water (1000 mL) and ethanol (2 × 50 mL) to afford IBX in 93–98% yield.3, 4 An additional ether wash (3 × 50 mL) is beneficial.5 Other oxidants such as potassium permanganate,2 chlorine,6 or oxone7 can also be employed. Handling, Storage, and Precautions: moisture stable, explosive under excessive heating (> 200 °C) or impact.8
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.001 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.018 | 0.016 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".