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Record W1953546126 · doi:10.1155/2003/702517

Norwalk Virus ‐‐ Off and Running

2003· article· en· W1953546126 on OpenAlexaffabout
JM Conly, BL Johnston

Bibliographic record

VenueCanadian Journal of Infectious Diseases and Medical Microbiology · 2003
Typearticle
Languageen
FieldMedicine
TopicViral Infections and Vectors
Canadian institutionsDalhousie UniversityQueen Elizabeth II Health Sciences CentreCalgary Laboratory ServicesUniversity of Calgary
Fundersnot available
KeywordsNorwalk virusVirologyVirusBiologyNorovirus

Abstract

fetched live from OpenAlex

H ospitals across Canada have been struggling with a series of outbreaks of viral gastroenteritis caused by the Norwalk virus (NV).Nursing homes, schools and hospitals in Alberta, British Columbia, New Brunswick and Ontario have been most affected, with additional outbreaks reported from Manitoba and Quebec (1-4).By the end of December 2002, in Edmonton's Capital Health Region, there were 42 outbreaks directly affecting more than 1000 individuals.Thirty outbreaks of viral gastroenteritis have been reported to Public Health in the Calgary Health Region since the beginning of October 2002, with 18 of these in December alone (2).In British Columbia from January to June 2002, more than 30 gastrointestinal illness outbreaks were found by reverse transcriptase polymerase chain reaction (RT-PCR) testing to be caused by Norwalk-like virus (NLV) (3).These outbreaks, involving both patients and staff, have occurred in various closed and semiclosed populations, including long term care facilities, assisted living sites, schools and acute care facilities.In most of the outbreaks where stool samples have been obtained for testing, NLV has been identified as the causative agent.This kind of outbreak activity usually signals a high amount of illness in the community and suggests that considerable under-reporting is occurring, with a resultant underestimation of the numbers of affected people.Many acute care hospitals across southern Ontario were forced to curtail visiting hours or temporarily close wards and emergency rooms in recent weeks to try to slow the spread of the virus (4).In addition, persistent outbreaks of gastrointestinal illness due to NLV among passengers and crew of cruise ships have been increasingly reported over the past few years.During the autumn of 2002, at least one large cruise ship was withdrawn from active service to provide an opportunity for a thorough environmental cleaning.What do we know about the NLV?What are the factors associated with its spread?The recent series of outbreaks provides an opportunity to review some of the epidemiology and features of NLV infections.In October 1968, an outbreak of acute gastroenteritis among students and teachers in an elementary school in Norwalk, Ohio was investigated by the Centers for Disease Control and Prevention (5).During a two-day period, 50% of the students and teachers (116 of 232) developed a gastrointestinal illness with a secondary attack rate of 32% among contacts of primary cases.The illness was characterized by nausea and vomiting in more than 90% of cases and diarrhea in 38%

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Commentary · Consensus signal: none
Teacher disagreement score0.867
Threshold uncertainty score0.267

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0010.001
Science and technology studies0.0060.001
Scholarly communication0.0030.001
Open science0.0010.002
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0150.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.236
Teacher spread0.229 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreCommentary

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations7
Published2003
Admission routes2
Has abstractyes

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