INFLUÊNCIA DO USO DE CRANBERRY NA SAÚDE SISTÊMICA E BUCAL / INFLUENCE OF THE USE OF CRANBERRY IN SYSTEMIC AND ORAL HEALTH
Bibliographic record
Abstract
Introdução: Cranberry é uma fruta vermelha nativa dos Estados Unidos e Canadá, cujas propriedades medicinais têm despertado o interesse tanto no campo da Medicina quanto da Odontologia. Objetivo: Este trabalho teve o propósito de abordar as propriedades e os meios pelos quais os componentes presentes no cranberry agem em relação a algumas alterações sistêmicas e bucais, através de revisão de literatura. Métodos: Foram consultadas as bases de dados Pubmed, Lilacs e Scielo, utilizando-se as palavras-chave: Cranberry, systemic health, periodontal diseases, periodontopathogen, biofilm and cytokines no período de 2004 a 2013. Resultados: Foram encontrados 52 artigos. Após análise, 45 trabalhos foram utilizados nesta revisão. Destes, 10 eram revisões de literatura, 26 estudos clínicos e 9 estudos in vitro. Cranberry possui um amplo espectro de ação, atuando como agente terapêutico/preventivo em doenças cardiovasculares, gastrointestinais e renais, bem como na inibição de formação do biofilme dental e a interação com enzimas associadas com sua formação, limitando a coagregação bacteriana, especialmente de espécies gram negativas, e impedindo a adesão tardia de periodontopatógenos ao biofilme. Conclusão: Cranberry, principalmente o componente fenólico proantocianidina do tipo A, possui excelentes propriedades terapêuticas para a saúde humana e atua como coadjuvante ao tratamento da doença periodontal.Palavras-chave: Sistema imunológico. Doenças periodontais. Biofilme. Tratamento.AbstractIntroduction: The cranberry is a red fruit native to the United States and Canada, whose medicinal properties have attracted the interest both in medicine and in dentistry. Objective: The aim of this study was to address the properties and the ways by which the components present in cranberry act in relation to some systemic and oral alterations, through literature review. Methods: It were consulted the Pubmed, Lilacs and Scielo databases, using the keywords Cranberry, systemic health, periodontal diseases, periodontopathogen, biofilm and cytokines, from 2004 to 2013. Results: were found 52 articles. After the analysis, 45 were used in this study. From these, 10 literature reviews, 26 clinical trials and 9 in vitro studies. The cranberry has a broad spectrum of action, acting as therapeutic/preventive agent in cardiovascular, gastrointestinal and renal diseases, as well as in the inhibition of dental biofilm formation and the interaction with enzymes associated with its formation, limiting bacterial coaggregation, especially of gram-negative species, and preventing late adherence of periodontopathogens to the biofilm. Conclusion: Cranberry, mainly the phenolic component proanthocyanidin type A, has excellent therapeutic properties for human health and acts as an adjunct to treatment of periodontal diseases.Keywords: Immune system. Periodontal diseases. Biofilm. Treatment.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.006 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.003 |
| Science and technology studies | 0.001 | 0.001 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".