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Record W1964856813 · doi:10.1145/1982185.1982209

Classifying microarray data with association rules

2011· article· en· W1964856813 on OpenAlexaff
Luiza Antonie, Kyrylo Bessonov

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGene expression and cancer classification
Canadian institutionsUniversity of Guelph
Fundersnot available
KeywordsAssociation rule learningComputer scienceAssociative propertyClassifier (UML)Data miningArtificial intelligenceMicroarray analysis techniquesSupport vector machineMachine learningPattern recognition (psychology)Feature (linguistics)Mathematics

Abstract

fetched live from OpenAlex

In this paper we investigate a method for classifying microarray data using association rules. Associative classifiers, classification systems based on association rules, show good performance level while being easy to read and understand. This feature is especially attractive for biological data where experts can read and validate the association rules. Relevant features are selected using Support Vector Machines with Recursive Feature Elimination. These features are discretized according to their relative expression levels (upregulated, downregulated or no change) and then they are used to build an associative classifier. The proposed combination proves highly accurate for the studied microarray data collection. In addition the classification rules discovered and employed in the classification process prove to be biologically relevant.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.284
Threshold uncertainty score0.207

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.056
GPT teacher head0.266
Teacher spread0.210 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations8
Published2011
Admission routes1
Has abstractyes

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