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Changes in Host and Parasite‐Derived Cellular and Extracellular Matrix Components in Developing Cysts of <i>Myxobolus pendula</i> (Myxozoa)

2002· article· en· W1966208237 on OpenAlexafffund
AMANDA A. MARTYN, Henry Hong, Maurice Ringuette, Sherwin S. Desser

Bibliographic record

VenueJournal of Eukaryotic Microbiology · 2002
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicMyxozoan Parasites in Aquatic Species
Canadian institutionsUniversity of Toronto
FundersNatural Sciences and Engineering Research Council of CanadaMinistry of Natural Resources
KeywordsBiologyParasite hostingMyxozoaExtracellular matrixMatrix (chemical analysis)Cell biologyUltrastructureMyxobolusConnective tissueAnatomyHost (biology)MicrobiologyFish <Actinopterygii>GillChemistryEcologyFishery

Abstract

fetched live from OpenAlex

Cysts of Myxobolus pendula from the gill arch of creek chub (Semotilus atromaculatus) were examined at various stages of development using light and electron microscopy. The subepithelial host connective tissue underwent dramatic changes, including degradation and remodelling of collagen and vascularisation, in response to the infection. Inflammatory cells lay in a fluid-filled space beneath the host's connective tissue and surrounded a distinctive parasite-derived matrix, composed of collagen fibril bundles embedded in cellular processes of the underlying secretory cells. This collagen matrix was resistant to degradation and invasion by leukocytes. Secretion of a matrix by M. pendula as a structural support, and a protective barrier against the host inflammatory cells is a novel observation for cyst-forming Myxosporea.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.095
Threshold uncertainty score0.853

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.022
GPT teacher head0.245
Teacher spread0.224 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations17
Published2002
Admission routes2
Has abstractyes

Explore more

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