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Record W1966492464 · doi:10.1007/s00439-014-1439-z

Large multiethnic Candidate Gene Study for C-reactive protein levels: identification of a novel association at CD36 in African Americans

2014· article· en· W1966492464 on OpenAlexaff
Jaclyn Ellis, Ethan M. Lange, Jin Li, Josée Dupuis, Jens Baumert, Jeremy Walston, Brendan J. Keating, Peter Durda, Ervin R. Fox, Yan Meng, Taylor Young, Deborah Farlow, Renate B. Schnabel, Carola Marzi, Emma K. Larkin, Lisa W. Martin, Joshua C. Bis, Paul L. Auer, Ramachandran S. Vasan, Stacey Gabriel, Monte S. Willis, James S. Pankow, George Papanicolaou, Jerome I. Rotter, Christie M. Ballantyne, Myron D. Gross, Guillaume Lettre, James G. Wilson, Ulrike Peters, Wolfgang Köenig, Russell P. Tracy, Susan Redline, Alex P. Reiner, Emelia J. Benjamin, Leslie A. Lange

Bibliographic record

VenueHuman Genetics · 2014
Typearticle
Languageen
FieldMedicine
TopicAdipokines, Inflammation, and Metabolic Diseases
Canadian institutionsUniversité de MontréalMontreal Heart Institute
FundersNational Institute on Minority Health and Health DisparitiesNational Center for Advancing Translational SciencesNational Center for Research ResourcesNational Institute of Neurological Disorders and StrokeNational Institute of Diabetes and Digestive and Kidney DiseasesNational Heart, Lung, and Blood InstituteDeutsche ForschungsgemeinschaftNational Institute on AgingNational Institutes of HealthBundesministerium für Bildung und ForschungEuropean Foundation for the Study of Diabetes
KeywordsHNF1AGenome-wide association studyBiologyCandidate geneGeneticsGenetic associationLocus (genetics)AlleleSNPSingle-nucleotide polymorphismGenotypeGeneInternal medicineBioinformaticsMedicine

Abstract

fetched live from OpenAlex
No abstract in any covered source. Its absence is recorded, not treated as a negative.

No abstract. This is not a gap in this database; OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.725
Threshold uncertainty score0.546

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.043
GPT teacher head0.326
Teacher spread0.283 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations38
Published2014
Admission routes1
Has abstractno

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