Effect of Selective Lymphoid Ablation on Rat Cardiac Allograft Survival
Bibliographic record
Abstract
Palladium-109-hematoporphyrin (Pd-H) contains a β-emitting isotope which when concentrated in the reticuloendothelial system causes total lymphoid and central bone marrow ablation. There is full recovery of tissue and blood cellularity within 60 days of its administration. A sublethal dose of Pd-H with a short course of rabbit antirat lymphocyte globulin results in specific tolerance to rat heart allografts across a minor histocompabihty barrier and significant prolongation of heart allografts across a major histocompatibility difference. Specific tolerance to donor strain was demonstrated by the acceptance of Fisher skin or heart by long-term Lewis recipients carrying old Fisher hearts (over 150 days) while they rapidly rejected ACI skin or heart allografts. The systemic irradiation with Pd-H in this study is as effective in immunosuppression as 800 rad total body irradiation and leads to no animal mortality.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".