Occult Primary Breast Cancer Presenting With Axillary Nodal Metastasis: Report of 3 Cases
Bibliographic record
Abstract
Occult primary breast cancer presenting as axillary metastasis is a very rare entity of breast cancer. Diagnosis and treatment management represent a real challenge in the absence of consensual attitude. We report 3 cases of occult breast cancer who presented with metastatic nodule in the axilla. Although histology identified a metastatic adenocarcinoma in the lymph nodes, mammography failed to detect the primary tumor. Immunohistochemistry showed that the biopsied lymph nodes were positive for both estrogen and progesterone receptors in all cases, suggesting the breast as the site of the primary tumor. Breast MRI was normal in addition to thoraco-abdomino-pelvic scan. Axillary dissection was performed with breast conservation followed by ipsilateral breast radiotherapy, then adjuvant chemotherapy. They are currently being treated with tamoxifen without evidence of disease with a median follow up of 8 months. doi: http://dx.doi.org/10.4021/jcgo42w
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.002 | 0.001 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.002 | 0.002 |
| Scholarly communication | 0.002 | 0.001 |
| Open science | 0.002 | 0.002 |
| Research integrity | 0.003 | 0.002 |
| Insufficient payload (model declined to judge) | 0.003 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".