Why this work is in the frame
A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.
Bibliographic record
Abstract
When prescribed appropriately and taken adherently, antiretroviral therapy can consistently and durably suppress HIV replication, potentially translating into years of near normal health for HIV-infected persons.However, presently available antiretrovirals are associated with a cluster of physical and metabolic symptoms termed HIV lipodystrophy.This article reviews the state of knowledge about the pathogenesis and treatment of the various manifestations of these adverse effects.Key words: adverse effects, antiretroviral therapy, HIV lipodystrophy -localized lipohypertrophy -dorsocervical ("buffalo hump") -anterior neck ("horse collar") -occipital -multiple cutaneous lipomata -breast enlargement 2. Metabolic -insulin resistance/glucose intolerance/dia betes mellitus -dyslipidemias -hypercholesterolemia -hypertriglyceridemia -hypertension -osteopenia -lactic acidosis LIPOHYPERTROPHY AND LIPOATROPHYAlthough sometimes occurring separately or with one manifestation being far more prominent than others, the combination of facial, limb, and buttock lipoatrophy, with central adiposity and less frequently a dorsocervical fat pad, remains among the most distressing and treatment-limiting adverse effects of available antiretrovirals.The psychosocial implications of HIV lipodystrophy may be significant.Lipodystrophic patients re-
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.005 | 0.006 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.008 | 0.003 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.001 | 0.033 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it