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Objective Evidence for the Reversibility of Nerve Injury in Diabetic Neuropathic Cachexia

2006· letter· en· W1970160866 on OpenAlexaff
Jaspreet Singh Grewal, Vera Bril, Gary F. Lewis, Bruce A. Perkins

Bibliographic record

VenueDiabetes Care · 2006
Typeletter
Languageen
FieldMedicine
TopicNeurological and metabolic disorders
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsMedicineDiabetes mellitusCachexiaNeuropathic painDiabetic neuropathyInternal medicineEndocrinologyAnesthesiaCancer

Abstract

fetched live from OpenAlex

Diabetic neuropathic cachexia is an acute complication of diabetes marked by such extreme pain and weight loss that, although exceptionally rare, it imparts major challenges in management and diagnosis. Little is known of the fundamental pathophysiologic features of the peripheral nervous system in this condition; for example, the symptomatic resolution that is classically observed may arise from either complete destruction of pain-transmitting nerve fibers or from their repair. To reconcile this issue, we report the first case to our knowledge that the nerve dysfunction is reversible. A 36-year-old woman presented with subacute hyperglycemic symptoms. Soon after initiation of insulin therapy …

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.002
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.106
Threshold uncertainty score0.854

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.002
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.001
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.030
GPT teacher head0.284
Teacher spread0.254 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2006
Admission routes1
Has abstractyes

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