Asymmetrical medial geniculate body volume in people with one eye
Bibliographic record
Abstract
Introduction. We have previously shown that people who have lost one eye early in life have enhanced sound localization (Hoover et al., 2011) and lack visual dominance (Moro & Steeves, 2011) compared to binocular and eye-patched viewing controls. People with one eye integrate auditory and visual information optimally, similar to controls, despite taking longer to localize unimodal visual stimuli (Moro, Harris & Steeves, 2013). Structurally, people with one eye have decreased lateral geniculate nuclei volume (LGN; thalamic visual relay station). However, this decrease is less severe in the LGN contralateral to the remaining eye, indicating altered structural development (Kelly, et al., 2013). The medial geniculate body (MGB; thalamic auditory relay station) plays a central role in auditory processing with both efferent and afferent tracts to primary auditory cortex (Schönwiesner, et al., 2007). Given the existing audiovisual processing differences and LGN changes in people with one eye, we investigated whether structural MGB changes are also present. Methods. MGB volume of adults who had undergone early unilateral eye enucleation was compared to binocularly intact controls. A series of 40 high-resolution proton density-weighted images were acquired with a 3T MRI scanner. Each series of scans were co-registered and averaged. Raters manually identified and traced MGB regions of interest in each participant. Results. People with one eye had a significant increase in MGB volume in the left compared to the right hemisphere independent of eye of enucleation. Controls did not exhibit this asymmetry. Conclusions. The volume asymmetry in the MGB in people with one eye may represent increased interaction between the left MGB and primary auditory cortex. This interaction could contribute to increased auditory attention, auditory spatial processing and other left hemisphere-dominant processing, including language. This asymmetry may reflect compensation for the loss of one half of visual inputs early in life. Meeting abstract presented at VSS 2014
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.004 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".