The Induction of Low Nocturnal Secretion of Melatonin Caused by Reverse Feeding Rhythms Depends on Availability of Macronutrient Diets
Why this work is in the frame
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Bibliographic record
Abstract
The present study investigated the effect of single chow diet and two-way dietary choice between a protein-rich and a carbohydrate-rich diet ingested during free access or daytime access (08.00-16.00 h) on the rhythms of ingestion and on nocturnal levels of serum melatonin and pineal N-acetyltransferase activity in rats. Animals with free access to the single or the choice diets displayed a circadian rhythmicity of total food intake with peaks at the beginning, the middle and the end of the dark phase. Rats fed the dietary choice displayed a preference for carbohydrate at the beginning, and a preference for protein at the middle and the end of the dark phase. Under daytime feeding access, both dietary conditions resulted in only one peak of total intake at the beginning of the access period. Rats fed the choice diets on the daytime feeding schedule initially preferred carbohydrate to protein but this preference disappeared subsequently. Nocturnal peaks of serum melatonin and pineal NAT activity were lower with daytime access to dietary choice compared to ad libitum access. The results suggest that in a two-way selection of macronutrients, feeding cycle can directly act on the rhythms expressed within the pineal gland.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it