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The effects of medial preoptic area and amygdala lesions on maternal behavior in the juvenile rat

2000· article· en· W1972685415 on OpenAlex
Gina Oxley, Alison S. Fleming

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

VenueDevelopmental Psychobiology · 2000
Typearticle
Languageen
FieldPsychology
TopicNeuroendocrine regulation and behavior
Canadian institutionsUniversity of Toronto
Fundersnot available
KeywordsJuvenileAmygdalaPsychologyHypothalamusDevelopmental psychologyEndocrinologyInternal medicinePhysiologyBiologyNeuroscienceMedicineEcology

Abstract

fetched live from OpenAlex

The present study was designed to determine whether the medial preoptic area (MPOA) and the amygdala (AMYG) are involved in the expression of "maternal" behavior in juvenile rats as they are in the adult. Juveniles show many behaviors that are similar to the maternal behaviors shown by the postpartum female rat. Whether these behaviors are social in function, as opposed to parental, and hence mediated by different mechanisms from those regulating adult maternal behavior is not known. To test the roles of the MPOA and AMYG in mediating these behaviors, 21-day-old female juvenile rats received MPOA, AMYG, or SHAM (MPOA/AMYG) lesions and were tested at 22 days of age for maternal and other responses to pups. Major findings demonstrate that MPOA lesions disrupt components of maternal behavior, including retrieving and nest building, while AMYG lesions facilitate these behaviors. These findings indicate striking similarities between the juvenile and rat brain for parental responding.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.457
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.018
GPT teacher head0.304
Teacher spread0.285 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it