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Record W1972761924 · doi:10.1139/s03-027

Quantification of a single population in a mixed microbial community using a laser integrated microarray scanner

2003· article· en· W1972761924 on OpenAlexvenueno aff
Stephen Callister, Héctor L. Ayala-del-Rı́o, Syed A. Hashsham

Bibliographic record

VenueJournal of Environmental Engineering and Science · 2003
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicAdvanced Biosensing Techniques and Applications
Canadian institutionsnot available
Fundersnot available
KeywordsBurkholderiaMicrobial population biologyPopulationScannerFluorophoreBiomass (ecology)MicrobiologyChemistryChromatographyMaterials scienceBacteriaBiologyFluorescenceMedicineOpticsEcology

Abstract

fetched live from OpenAlex

A laser integrated microarray scanner was used to quantify and compare the biomass of Burkholderia cepacia G4 alone, mixed with Afipia sp., and mixed with a trichloroethylene and phenol degrading community. Samples containing B. cepacia G4 were placed in 3-mm diameter wells on gelatin coated glass slides then fixed and immunofluorescently labeled using an IgG conjugate with an attached AlexaTM 546 fluorophore. Linearity and sensitivity of the scanner for biomass quantification were established, and a lower detection limit of 2–5 mg L–1 (103–104 cells mL–1) was calculated. Growth of B. cepacia G4 alone and in the presence of the TCE degrading community was measured using the scanner. Results suggest that the microarray scanner can be used to quantify the biomass of a single population in a dense mixed microbial community. Key words: biomass, Burkholderia cepacia G4, fluorescent antibody, microarray scanner, mixed community.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.009

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0010.001
Meta-epidemiology (narrow)0.0010.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.001
Science and technology studies0.0000.000
Scholarly communication0.0010.001
Open science0.0010.001
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.0030.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.231
Teacher spread0.219 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations2
Published2003
Admission routes1
Has abstractyes

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