Is polysomnography predictive of respiratory complications post adenotonsillectomy in children?
Bibliographic record
Abstract
60, 120 and 240 min after administration of diclofenac, centrifuged and the supernatant stored at )80 °C until analysis.Serum concentrations of dicolfenac were measured by reverse phase high performance liquid chromatography with ¯uroimetric detection.Results There were no adverse effects following rectal administration of diclofenac 2 mgákg )1 and no incidence of primary or secondary bleeding.Individual serum drug concentration ®tted a biexpontential function and could be described in all patients.Pharmacokinetic parameters are expressed in Table 1 (mean SD).Discussion t max after rectal diclofenac varied from 30 to 60 min which is similar to that reported in adults (1).t 1/2B (71 20 min) values were similar to values after intravenous infusion administration in children ( 2).In this study, C max of 2.38 mgál )1 was recorded in comparison to a previous 1.6 mgál )1 report after 1.5 mgákg )1 in children after oral administration (3).C max is considerably lower than adult values possibly due to difference in V d .Rectal dicofenac pharmacokinetics mirrors adult elimination values and time to maximum concentrations.Diclofenac in children is rapidly absorbed after rectal administration and may be administered at induction of anaesthesia to provided adequate postoperative analgesia in children undergoing TA surgery.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".