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Record W1974656280 · doi:10.3899/jrheum.140613

A Deadly Complication of Systemic Lupus Erythematosus

2014· letter· en· W1974656280 on OpenAlexvenueno aff
Marvin I. Schwarz

Bibliographic record

VenueThe Journal of Rheumatology · 2014
Typeletter
Languageen
FieldMedicine
TopicSystemic Lupus Erythematosus Research
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineComplicationDiffuse alveolar hemorrhageVasculitisSystemic vasculitisSystemic diseaseSystemic lupus erythematosusCohortAntiphospholipid syndromeMechanical ventilationInternal medicineDiseaseThrombosis

Abstract

fetched live from OpenAlex

Diffuse alveolar hemorrhage (DAH), often a catastrophic event resulting in acute respiratory failure, occurs in the setting of the collagen vascular diseases, in particular systemic lupus erythematosus (SLE). There are a number of other systemic conditions that may result in this complication, including any of the systemic vasculitides, antibasement membrane antibody disease, medications that result in vasculitis, antiphospholipid syndrome, various coagulopathies, thrombocytopenia from any cause, and less frequently, severe viral infections1. In this issue of The Journal Martinez-Martinez, et al describe 50 subjects with SLE, both adults and juveniles, who experienced 57 episodes of DAH2. This represents the largest collection of patients with this SLE complication. There were no differences in outcomes between juveniles (< 18 yrs) and adults. In the adult group 90% were women and the mean age for the entire cohort was 23 years. Overall mortality was 42%, and not unexpectedly, the sicker patients, i.e., those requiring mechanical ventilation and those with infections, renal dysfunction, hypocomplementemia, and … Address correspondence to Dr. Schwarz, 12700 East 19th Ave. C272, Aurora, Colorado 80045, USA. E-mail: Marvin.Schwarz{at}UCDenver.edu

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.004
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Case report · Consensus signal: Case report
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.003
Threshold uncertainty score0.007

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.004
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0000.000
Science and technology studies0.0010.001
Scholarly communication0.0010.001
Open science0.0000.000
Research integrity0.0030.003
Insufficient payload (model declined to judge)0.0020.002

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.031
GPT teacher head0.296
Teacher spread0.266 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designCase report
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations0
Published2014
Admission routes1
Has abstractyes

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