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Record W1974883772 · doi:10.1126/science.288.5475.2349

Accommodating Phylogenetic Uncertainty in Evolutionary Studies

2000· article· en· W1974883772 on OpenAlexaff
John P. Huelsenbeck, Bruce Rannala, John P. Masly

Bibliographic record

VenueScience · 2000
Typearticle
Languageen
FieldEarth and Planetary Sciences
TopicEvolution and Paleontology Studies
Canadian institutionsUniversity of Alberta
FundersNational Human Genome Research Institute
KeywordsPhylogenetic treePhylogeneticsEvolutionary biologyPhylogenetic comparative methodsBayesian probabilityNatural selectionBiologyInferenceBayesian inferenceStatistical inferenceSelection (genetic algorithm)Computational phylogeneticsComputer sciencePhylogenetic networkArtificial intelligenceStatisticsMathematicsGeneticsGene

Abstract

fetched live from OpenAlex

Many evolutionary studies use comparisons across species to detect evidence of natural selection and to examine the rate of character evolution. Statistical analyses in these studies are usually performed by means of a species phylogeny to accommodate the effects of shared evolutionary history. The phylogeny is usually treated as known without error; this assumption is problematic because inferred phylogenies are subject to both stochastic and systematic errors. We describe methods for accommodating phylogenetic uncertainty in evolutionary studies by means of Bayesian inference. The methods are computationally intensive but general enough to be applied in most comparative evolutionary studies.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.107
metaresearch head score (Gemma)0.456
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Theoretical or conceptual · Consensus signal: Theoretical or conceptual
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.107
Threshold uncertainty score0.565

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.1070.456
Meta-epidemiology (narrow)0.0020.002
Meta-epidemiology (broad)0.0030.002
Bibliometrics0.0050.007
Science and technology studies0.0030.006
Scholarly communication0.0050.010
Open science0.0060.010
Research integrity0.0060.008
Insufficient payload (model declined to judge)0.0020.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.290
Teacher spread0.253 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designTheoretical or conceptual
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations371
Published2000
Admission routes1
Has abstractyes

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