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Record W1974912623 · doi:10.1002/ddr.10371

The Estonian Genome Project

2004· article· en· W1974912623 on OpenAlexaboutno aff
Andres Metspalu

Bibliographic record

VenueDrug Development Research · 2004
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicGenetics, Bioinformatics, and Biomedical Research
Canadian institutionsnot available
FundersExxonMobil Research and Engineering Company
KeywordsEstonianEuropean unionPopulationGovernment (linguistics)LegislaturePolitical scienceExcellencePublic administrationPublic relationsLibrary scienceBusinessEnvironmental healthMedicineComputer scienceLaw

Abstract

fetched live from OpenAlex

Abstract The Estonian Genome Project (EGP) is a large population‐based databank that was established with health records and biological samples from a large portion of the population for use in biomedical and genetic research to improve the future of public health care in Estonia. A nonprofit foundation, the Estonian Genome Foundation presented the EGP to the Estonian government in June 2000 leading to a new legislative act, the “Human Genes Research Act,” that provides a road map for future gene‐related activities and guidelines for the oversight of the databank via a Supervisory Board, Ethics Committee, and Scientific Advisory Board. Unlike other gene discovery efforts, participants in population‐based projects are not selected by specific disease type but rather via a random sampling process. The unbiased nature of the recruitment process provides a more accurate measure of the disease risk provided by particular genetic variants and is anticipated to collect 100,000 samples by the end of 2007. The EGP is part of the first international consortia, P3G, set up between Cart@gene from Canada and GenomEUtwin, a FP5‐funded project coordinated by the University of Helsinki, Finland. With Estonia joining the European Union in 2004, the EGP will also function to build scientific excellence in Estonia. Drug Dev. Res. 62:97–101, 2004. © 2004 Wiley‐Liss, Inc.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.004
metaresearch head score (Gemma)0.008
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.100
Threshold uncertainty score0.335

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0040.008
Meta-epidemiology (narrow)0.0020.000
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0070.013
Science and technology studies0.0010.000
Scholarly communication0.0040.001
Open science0.0020.003
Research integrity0.0010.001
Insufficient payload (model declined to judge)0.1000.047

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.041
GPT teacher head0.349
Teacher spread0.308 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations41
Published2004
Admission routes1
Has abstractyes

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