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Record W1975529510 · doi:10.1039/c0an00371a

Confocal Raman microscopy: common errors and artefacts

2010· article· en· W1975529510 on OpenAlexaff
Neil Everall

Bibliographic record

VenueThe Analyst · 2010
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicSpectroscopy Techniques in Biomedical and Chemical Research
Canadian institutionsIntertek (Canada)
Fundersnot available
KeywordsRaman spectroscopyMicroscopyConfocalMicroscopeConfocal microscopyOpticsProfiling (computer programming)Raman microscopeResolution (logic)NanotechnologyMaterials scienceComputer scienceArtificial intelligencePhysicsRaman scattering

Abstract

fetched live from OpenAlex

Confocal Raman microscopy is a powerful tool for research and analysis in the chemical, materials and life sciences, particularly for non-destructive depth profiling of transparent systems. Unfortunately, many Raman microscopes are not optimally configured for this purpose, and so yield unnecessarily low signal-to-noise spectra with poor spatial resolution and grossly incorrect depth scales. This review discusses the aberrations and artefacts that can arise and describes how these can be avoided by adhering to a few basic principles that are well known to optical microscopists but which were largely ignored in the spectroscopic community for many years.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.021
metaresearch head score (Gemma)0.049
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Methods · Consensus signal: Methods
Teacher disagreement score0.021
Threshold uncertainty score0.113

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0210.049
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0020.001
Bibliometrics0.0040.004
Science and technology studies0.0020.005
Scholarly communication0.0030.003
Open science0.0020.004
Research integrity0.0040.003
Insufficient payload (model declined to judge)0.0030.003

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.006
GPT teacher head0.322
Teacher spread0.316 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreMethods

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations197
Published2010
Admission routes1
Has abstractyes

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