Effect of Polysaccharides on Enteric Mucosal Immune Response in Rats
Bibliographic record
Abstract
The effect of ginseng polysaccharide and Polyporus umbellatus polysaccharide on T-lymphocytes in enteric mucosal lymphocytes in rats, including healthy rats, those with collagen induced arthritis, and with C26 colon carcinoma were explored. For this study peripheral blood mononuclear cells (PBMC), peyer's patch lymphocyte (PPL), intraepithelial lymphocyte (IEL), and lamina propria lymphocyte (LPL) of SD rats were isolated. These lymphocytes were co-cultured with ginseng polysaccharide and Polyporus umbellatus polysaccharide in different dosages. The TNF-α and IFN-γ in supernatants were measured with ELISA. Ginseng polysaccharide and Polyporus umbellatus polysaccharide can regulate the level of TNF-α and IFN-γ in the supernatant of PBMC and PPL; Polyporus umbellatus polysaccharide in some dosages can increase the level of TNF-α and IFN-γ in supernatant of IEL; Ginseng polysaccharide and Polyporus umbellatus polysaccharide can decrease the level of TNF-α and IFN-γ in supernatant of LPL. Ginseng polysaccharide and Polyporus umbellatus polysaccharide can regulate the function of lymphocytes in the enteric mucosal immune system.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".