Bibliographic record
Abstract
Most common adverse reactions to warfarin are fatal and nonfatal hemorrhage from any tissue or organ. Despite bleeding complications being the most feared concern, non-bleeding events can also occur from warfarin therapy. These non-bleeding events, which account for less than 1%, include but are not limited to skin necrosis and dermatological hypersensitivity reactions. We describe a rare case of “warfarin allergy” in a 77-year-old female patient admitted for coronary bypass grafting and mitral/aortic valve replacement. The patient came with a history of valvular heart disease, embolism (occlusion of distal superficial femoral artery) and atrial fibrillation with documented “warfarin allergy” described as dermatitis and anaphylaxis witnessed during earlier hospital admission. Given double valve replacement and atrial fibrillation (CHA 2 DS 2 -VASc score of 9), she was deemed a candidate for lifelong warfarin. Significant renal impairment and recent valve replacement narrowed the choice of anticoagulant to warfarin. To rule out the possibility of dye allergy, patient was re-challenged with dye free warfarin with close monitoring. Patient was able to tolerate dye free (white) warfarin with no allergic manifestation. The purpose of this report is to increase awareness of possibility of allergic reaction to dye in medications and recommend possibility of dye free medications as an option in such cases. J Hematol. 2014;3(4):116-117 doi: http://dx.doi.org/10.14740/jh173w
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.003 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.007 | 0.002 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".