Serum thyroid hormone concentrations and thyroid histomorphology as biomarkers in bowhead whales (Balaena mysticetus)
Bibliographic record
Abstract
Serum thyroid hormone (TH) concentrations have been used alone or with other measurements to assess health status or effects of toxicant exposure in marine mammals. Histological sections from thyroid glands of the bowhead whale ( Balaena mysticetus L., 1758) were examined in conjunction with serological TH analyses. Serum was assayed for total and free triiodothyronine and total and free thyroxine via radioimmunoassay. Histomorphology of thyroid tissue was assessed by light microscopy and the utilization of an epithelial-follicular index (EFI). Age, sex, or season did not significantly affect serum TH levels. However, TH concentrations in pregnant or lactating females were found to be significantly lower than in the other sex and reproductive groups investigated. The EFI and epithelial height (EH) were greater in spring subadult and adult whales compared with those that were landed in the fall. No correlation was found between serum TH concentrations and serum, blubber, or liver levels of select polychlorinated biphenyl metabolites and organochlorine congeners examined. Low variability in concentrations of the serum THs across age, season, and sex and reproductive groups supports the existence of strong homeostatic mechanisms for maintaining TH concentrations in these presumably healthy animals. Departures from these ranges may indicate a disturbance in these regulatory mechanisms and may be a useful indication of toxicity or other health disorders.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".