Exercise Intolerance in Pulmonary Arterial Hypertension. The Role of Cardiopulmonary Exercise Testing
Bibliographic record
Abstract
A 23-year-old, never-smoking woman who was physically fit since childhood developed progressive intolerance to exertion in the preceding 12 months. She was diagnosed with severe pulmonary arterial hypertension due to an atrial septal defect and subsequently underwent cardiopulmonary exercise testing. An understanding of exercise physiology was essential in identifying the pathophysiological causes of her dyspnea on exertion and assessing the response to pharmacological therapy. A white, 23-year-old woman sought medical attention complaining of progressive exercise limitation due to shortness of breath and “fatigue,” which started about a year earlier. She denied cough, wheezing, or any other respiratory symptoms. She reported being physically active since childhood, but had become mildly limited during daily life activities (New York Heart Association Class II). She denied smoking, significant occupational or environmental exposures, use of illicit drugs, and exposure to drugs with known lung toxicity. She weighed 50 kg and her height was 157 cm.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.005 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.001 |
| Scholarly communication | 0.001 | 0.002 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.002 | 0.002 |
| Insufficient payload (model declined to judge) | 0.002 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".