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Stage-Specific Optimization of Activin/Nodal and BMP Signaling Promotes Cardiac Differentiation of Mouse and Human Pluripotent Stem Cell Lines

2011· article· en· 1,176 citations· W1977025496 on OpenAlex· 10.1016/j.stem.2010.12.008

Why is this work in the frame?

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

Canadian affiliationAn author listed a Canadian institution. This is the only route the usual frame has.
Canadian funderA Canadian agency funded it. The work may carry no Canadian affiliation at all.

Machine scores (provisional)

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Opus teacher head0.023
GPT teacher head0.224
Teacher spread
0.201 · how far apart the two teachers sit on this one work
Validation status
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Abstract

No abstract. This is not a gap in this database — OpenAlex has none either. 23.3% of the frame is in this state, and the screen finds HALF as much metaresearch here, so the absence is a measured bias rather than a missing field.

The record

Venue
Cell stem cell
Topic
Pluripotent Stem Cells Research
Field
Biochemistry, Genetics and Molecular Biology
Canadian institutions
SickKids FoundationUniversity of TorontoUniversity Health Network
Funders
National Heart, Lung, and Blood InstituteCanadian Institutes of Health ResearchNational Institutes of Health
Keywords
BiologyMesodermNodal signalingNODALInduced pluripotent stem cellEmbryonic stem cellCell biologyStem cellCellular differentiationActivin receptorSignal transductionGeneticsGene
Has abstract in OpenAlex
no