Isolation of a Low Molecular Weight Constituent from Kentucky Blue Grass Pollen Possessing Carrier Activity of High Molecular Weight Constituent(s)
Bibliographic record
Abstract
An immunologically active fraction, designated as C-I-3 was isolated from the dialysate of the aqueous extract of defatted Kentucky Blue Grass pollen by differential dialysis and gel filtration. This fraction was shown to consist of a glycoprotein with a molecular size corresponding to 4,800 daltons and with a pI value of 3.6, and to contain all amino acids except cysteine. The intraperitoneal administration of C-I-3 in saline into mice or rats prior to their immunization with the nondialyzable constituents of the aqueous extract of Kentucky Blue Grass (i.e., the retentate, R) in presence of Al(OH)3 resulted in the enhanced production of anti-R IgE antibodies. The enhancement of the anti-R murine IgE response was shown in adoptive cell transfer experiments to be due to the generation of R-specific T helper cells. Hence, it is suggested that the structural elucidation of C-I-3 may prove useful in establishing the nature of carrier determinant(s) of the major allergenic components of Kentucky Blue Grass pollen.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".