Les cellules souches de la moëlle osseuse au secours de la maladie d’Alzheimer
Bibliographic record
Abstract
> La maladie d’Alzheimer est la forme la plus courante de demence chez les humains. Cette maladie est caracterisee par la presence de depots de peptide β-amyloide (βA) dans le parenchyme du cerveau et le reseau microvasculaire. Ces depots extracellulaires sont aussi connus sous le nom de plaques amyloides ou plaques seniles. Le developpement des plaques va de pair avec le deficit cognitif, cependant le mecanisme exact en cause dans la mort des neurones qui s’ensuit et qui marque la maladie reste aujourd’hui encore hypothetique et fortement debattu comme en temoignent les nombreuses publications sur le sujet. Les corps amyloidiens sont toujours accompagnes de microglies, les cellules immunitaires du cerveau.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.002 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.001 |
| Science and technology studies | 0.001 | 0.005 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.002 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".