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Record W1978043246 · doi:10.1212/wnl.0b013e3182840cd9

MR spectroscopy in pediatric Wernicke encephalopathy

2013· article· en· W1978043246 on OpenAlexaff
Lance H. Rodan, Navin Kumar Mishra, Ingrid Tein

Bibliographic record

VenueNeurology · 2013
Typearticle
Languageen
FieldMedicine
TopicAlcoholism and Thiamine Deficiency
Canadian institutionsHospital for Sick Children
Fundersnot available
KeywordsThiamineThiamine deficiencyEncephalopathyWernicke EncephalopathyMedicineWernicke's encephalopathyAtaxiaLactate dehydrogenaseNystagmusInternal medicinePathologyGastroenterologyEndocrinologyAnesthesiaChemistryBiochemistryRadiologyEnzymePsychiatry

Abstract

fetched live from OpenAlex

The patient is a 7-year-old girl with a history of repaired gastroschisis and short gut syndrome. She presented with a 4-day history of progressive encephalopathy, truncal ataxia, and omnidirectional gaze-evoked nystagmus. Peripheral lactate was 7.1 mmol/L. Serum thiamine level was decreased (<5 nmol/L). Brain magnetic resonance with spectroscopy is shown in the figure. A clinical diagnosis of Wernicke encephalopathy was made. The patient was started on thiamine and demonstrated a rapid clinical recovery. Peripheral lactate normalized within 1 day. Increased lactate has been reported in thiamine deficiency, presumed secondary to the role of thiamine as a cofactor for the pyruvate dehydrogenase complex and α-ketoglutarate dehydrogenase.1

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesInsufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.020
Threshold uncertainty score0.999

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.253
Teacher spread0.242 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations10
Published2013
Admission routes1
Has abstractyes

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