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Record W1979498941 · doi:10.1102/1470-7330.2012.0025

Nuclear oncology in Cancer Imaging 2011

2012· editorial· en· W1979498941 on OpenAlex

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

aboutThe title or abstract carries a Canadian signal from the geographic lexicon.
no affNo Canadian affiliation: this work is invisible to an affiliation-only frame.
No Canadian affiliation. An affiliation-only frame, the usual design, would never have seen this work. It is one of the works that make the case for inverting the frame.

Bibliographic record

VenueCancer Imaging · 2012
Typeeditorial
Languageen
FieldMedicine
TopicNeuroendocrine Tumor Research Advances
Canadian institutionsnot available
Fundersnot available
KeywordsMedicineNeuroendocrine tumorsSomatostatin receptorPositron emission tomographyLung cancerNuclear medicineLymphomaRadionuclide therapyOncologyRadiologyInternal medicineSomatostatin

Abstract

fetched live from OpenAlex

Nuclear oncology featured strongly in the 2011 issue of Cancer Imaging with 5 reviews, 2 original articles and 3 case reports. Many articles described diagnostic applications of novel or emerging tracers. Stomatostatin receptor scintigraphy provided the focus of 2 original articles and a case report. Jindal et al.[1] (New Delhi, India) evaluated of the role of [18F]FDG-PET/CT and [68Ga]DOTATOC-PET/CT in 20 patients with pulmonary carcinoids and concluded that the different uptake patterns of the 2 tracers and the ratio of measured uptake may be helpful in differentiating between typical and atypical carcinoids. A case report of concomitant lung and gastroenteropancreatic neuroendocrine tumours by Kaemmerer et al.[2] (Bad Berka, Germany) highlighted the utility of gallium-68 somatostatin receptor PET/CT based detection and follow-up of neuroendocrine tumours. A study by Beauregard et al.[3] (Quebec City, Canada) described the development of a quantitative 177Lu SPECT imaging method using a commercially available SPECT/CT system. The authors highlighted the potential for the technique to yield more accurate dosimetry estimates and facilitate therapeutic response assessment for therapeutic agents such [177Lu]octreotate. A case report by Holter et al.[4] (Oklahoma City, USA) illustrates the utility of [18F]fluorothymidine-PET imaging in the diagnosis of leptomeningeal involvement with diffuse large B-cell lymphoma. Tracers such as [18F]fluorthymidine that depict proliferation, as well as hypoxia markers such as 18F-labelled fluorinated imidazoles, are also highlighted by ICIS fellow Wim Oyen (Nijmegen, The Netherlands) in his review of the prospects for molecular imaging in the Special Issue in which he explores the role of PET beyond FDG for patient selection, treatment modification and adaptation and early response monitoring following radiotherapy[5]. The use of the more widely used PET tracer [18F]fluorodeoxyglucose is considered in 3 articles related to thoracic malignancies. Kaira et al.[6] (Shizuoka, Japan) systematically reviewed the role of [18F]FDG-PET in thymic epithelial tumours and concluded that [18F]FDG-PET may be useful in differentiating thymomas and thymic carcinomas. A case report by Akosman et al.[7] (Istanbul, Turkey) entitled Unicentric mixed variant Castleman disease associated with Hashimoto disease: the role of PET/CT in staging and evaluating response to the treatment proposes a potential role for [18F]FDG-PET/CT not only in staging Castleman disease but also in the assessment of treatment response. In the Special Issue, ICIS fellow Sheila Rankin (London, UK) reviews the value of [18F]FDG-PET/CT in oesophageal cancer highlighting the technique’s accepted role as an adjunct to conventional imaging for the staging of oesophageal cancer, for response assessment and identification of recurrent disease[8]. An issue that potentially affects imaging with any PET tracer is the clinical significance and management of lesion motion due to respiration during PET/CT scanning, which was reviewed by Callahan et al.[9] (Melbourne, Australia). They illustrate how accurate characterization of PET-avid disease in areas of high respiratory motion can be challenging and describe different approaches that have been used to address the issue of respiratory motion in PET/CT. The continuing development of conventional gamma imaging in oncology is shown by Dizdarevic and Peters[10] (Brighton, UK) who review the imaging of multidrug resistance in cancer with an emphasis on [99mTc]MIBI scintigraphy, illustrating the opportunities for cost-effectively guiding individualized treatment in an era of personalized medicine. These Cancer Imaging articles testify to the ongoing importance of nuclear medicine in the imaging and treatment of cancer.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesMeta-epidemiology (narrow), Research integrity, Insufficient payload (model declined to judge)
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: Not applicable
GenreCandidate signal: Editorial · Consensus signal: Editorial
Teacher disagreement score0.055
Threshold uncertainty score1.000

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0010.001
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0010.000
Research integrity0.0000.003
Insufficient payload (model declined to judge)0.0050.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.025
GPT teacher head0.408
Teacher spread0.384 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it