Occupational asthma after exposure to<i>ortho</i>-phthalaldehyde (OPA)
Bibliographic record
Abstract
Ortho -phthalaldehyde (OPA) is an aromatic dialdehyde that has largely replaced glutaraldehyde as a new high-level disinfectant for heat-sensitive medical devices, including endoscopes. It is a low-molecular-weight chemical with in vivo dermal and respiratory sensitising properties.1 ,2 Reports of immunological reactions have been reported in workers exposed to OPA-disinfected cystocopes.3 We describe the case of a 55-year-old woman who consulted at the emergency department with dyspnoea, wheezing, conjunctival redness and low peak expiratory flow. She had been promoted to the endoscopic sterilisation service of a regional hospital 2 months earlier, where OPA (Cidex OPA) was used for disinfection of endoscopes. Symptoms …
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.013 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; both teacher heads agree on what is shown here.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".