Release of Gastric Inhibitor from the Intestine of Dogs Infused Intravenously with Sodium Oleate
Bibliographic record
Abstract
We found previously that intravenous infusion of sodium oleate induced inhibition of pentagastrin-stimulated gastric secretion in canine Heidenhain pouches. In the present study we attempted to verify the hypothesis that such intravenous infusion provoked Extract of intestinal mucosa release, from intestinal mucosa, of an enterogastrone-like inhibitor. Lyophilized extracts of canine intestinal secretion or mucosa were prepared using dogs infused for 6 h with saline or with sodium oleate. These extracts weren then assayed for their inhibitory action by intravenous infusion into Heidenhain pouches of dogs, stimulated with pentagastrin. When solvent or extracts prepared from intestinal juice or gut mucosa of dogs infused with saline were tested, no inhibition of gastric acid occurred. When extracts prepared from dogs infused with oleate were assayed, gastric acid secretion was inhibited. We concluded that intravenous infusion of fat results in the release of a gastric inhibitor of intestinal origin which behaves as an enterogastrone. This may be a most reasonable explanation of the action of intravenous sodium oleate on gastric secretion.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.001 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".