Perioperative Care of an Adolescent With 11-Beta-Hydroxylase Deficiency
Bibliographic record
Abstract
Congenital adrenal hyperplasia (CAH) is the result of an autosomal recessive disorder affecting one of the several steps required for the synthesis of cortisol from cholesterol by the adrenal cortex. 11?-hydroxylase deficiency accounts for 5-8% of all cases of CAH with an incidence estimated at 1 in 100,000 - 200,000 newborns. We present a 14-year-old girl with CAH due to 11?-hydroxylase deficiency who presented for surgical treatment of virilization. The perioperative care of patients with CAH should address issues related to the deficient and excessive production of specific mineralocorticoids and corticosteroids by the adrenal cortex. The authors discuss the perioperative implications of the disorder and review previous reports of anesthetic care for such patients. J Med Cases. 2015;6(5):221-225 doi: http://dx.doi.org/10.14740/jmc2125w
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.001 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.000 |
| Science and technology studies | 0.001 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.000 | 0.001 |
| Research integrity | 0.001 | 0.002 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".