Impedance cardiographic waveforms in children: Involvement in left ventricular ejection time determination during anesthesia
Bibliographic record
Abstract
OBJECTIVE: The physiologic basis of the impedance cardiographic (ICG) signal is still a matter of debate. An accurate determination of left ventricular ejection time (LVET) is needed to calculate stroke volume. In children, several shapes of the ICG signal are observed during anesthesia or in critical care. The aim of this study was to determine the relationship between the shape of the ICG signal and various morphologic and hemodynamic determinants obtained with Doppler echocardiography to highlight the effect of the various shapes in the accuracy of LVET determination. DESIGN: Prospective study. SETTING: Pediatric surgery in a university hospital. PATIENTS: 103 children, ASA physical status I or II. INTERVENTIONS: General anesthesia for elective surgery. Measurements: Electrocardiography, ICG, and Doppler echocardiography were recorded simultaneously. Classic hemodynamic variables, such as heart rate, LVET, stroke volume, or systemic vascular resistance, were measured or calculated. A mathematical model of the ICG signal was used to determine the shape of the ICG signal and its potential relationship to various morphologic and hemodynamic determinants. The ICG signal shape was then modeled with the normalized amplitudes (NHA) and phase (NHP) of the three harmonics of the fundamental signal. Analysis was performed with a multiple correspondence analysis. RESULTS: ICG method LVET did not significantly correlate with LVET determined with Doppler or with heart rate. NHA and NHP of the ICG signal were not significantly related to LVET determined with Doppler or to stroke volume. NHA were linked to heart rate and the relative length of the cardiac diastolic period. CONCLUSION: The absence of relationship between LVET determined with Doppler and the main variables defining the shape of the ICG signal highlight the relative limit of stroke volume determination with ICG method. The involvement of the arterial compliance in the ICG signal shape can be discussed in regard to the links between NHA and both heart rate and the relative length of the cardiac diastolic period, respectively.
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How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.006 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.001 | 0.001 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.001 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".