Self-Assembly of Frayed Wires and Frayed-Wire Networks: Nanoconstruction with Multistranded DNA
Bibliographic record
Abstract
New types of self-assembled 2-D and 3-D DNA networks are presented and characterized using scanning force microscopy. The building blocks of these networks are guanine-rich DNA sequences, d(A 15 G 15 ) and biotinylated-d(A 15 G 15 ). These sequences self-assemble into high molecular weight structures, frayed wires, that are composed of a multistranded guanine core with single-stranded adenosine tracts emanating from the core at ∼6 nm intervals. Avidin peroxidase was attached to the biotinylated frayed wires with retention of activity, demonstrating that these structures can be used as scaffolds to support multiple copies of non-DNA molecules. Finally, the frayed wires were linked together with CT 15 or T 15 to form large 2- and 3-dimensional networks.
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How this classification was reachedexpand
Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one teacher head, not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".