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Record W1984236710 · doi:10.1159/000136888

The Effect of Drugs on the Electrical and Mechanical Activity of the Isolated Porcine Stomach

2008· article· en· W1984236710 on OpenAlexaff
K. Kowalewski, S Zajaç, A. Kolodej

Bibliographic record

VenuePharmacology · 2008
Typearticle
Languageen
FieldMedicine
TopicGastrointestinal motility and disorders
Canadian institutionsAlberta Medical AssociationUniversity of Alberta
Fundersnot available
KeywordsHexamethoniumPentagastrinAtropineStomachCholinergicAcetylcholinePharmacologyEndocrinologyInternal medicineMechanism of actionMedicineChemistryGastric acidBiochemistry

Abstract

fetched live from OpenAlex

Electrical and mechanical activity was recorded from totally isoltted porcine stomachs perfused with homologous blood, The electrical control activity, response activity, and mechanical reaction to various hormones and drugs stimulationg these activities were recorded. The drugs were injected directly into the gastric artery of the isolated organ. Normal response to cholinergic stimulants and to pentagastrin was observed. The effect of blockers such as atropine, hexamethonium and tetrodotosin on the action of stimulants was also assessed. The results of this study suggest that the release of acetylcholine is involved in the mechanism of action of pentagastrin. They also demonstrate the usefulness of the isolated porcine stomach approach to the study of gastric myoelectrical and mechanical activity.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Bench or experimental · Consensus signal: Bench or experimental
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.205
Threshold uncertainty score0.163

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.012
GPT teacher head0.285
Teacher spread0.273 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designBench or experimental
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations3
Published2008
Admission routes1
Has abstractyes

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