The Value of Single-Dose Therapy to Diagnose the Site of Urinary Infection
Bibliographic record
Abstract
Several single dose regimens have been shown to cure 90 percent of women with acute cystitis in whom infection is confined to the bladder. About 25 percent of women with acute cystitis and approximately one-half with asymptomatic infection have organisms originating from one or both upper urinary tracts. Effective single dose regimens such as trimethoprim-sulfamethoxazole, amoxicillin, and trimethoprim alone, cure between 40 and 60 percent of upper tract infections in women with renal involvement, who present with acute cystitis or with asymptomatic bacteriuria. Five studies have shown that single dose failure in women with acute cystitis or asymptomatic bacteriuria is a specific predictor of upper tract infection. It is also sensitive (60-80 percent) in predicting upper tract pathology. The evidence to date favours the hypothesis that failure of single dose cure following treatment with an effective single dose regimen in adult women who have asymptomatic bacteriuria or acute cystitis, identifies a subset of women who require further investigation of the urinary tract.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.001 |
| Meta-epidemiology (narrow) | 0.001 | 0.000 |
| Meta-epidemiology (broad) | 0.002 | 0.001 |
| Bibliometrics | 0.002 | 0.002 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.001 | 0.001 |
| Open science | 0.001 | 0.000 |
| Research integrity | 0.001 | 0.001 |
| Insufficient payload (model declined to judge) | 0.003 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".