One-dimensional jumping optical tweezers for optical stretching of bi-concave human red blood cells
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Bibliographic record
Abstract
We report the experimental demonstration of optical stretching of individual bio-concave human red blood cells (RBCs) with one-dimensional jumping optical tweezers. We trapped a RBC in isotonic buffer solution in a conventional stationary single-beam gradient-force optical trap and discretely scanned the trapping beam with an acousto-optic modulator such that the focal point of the trapping beam jumped back-and-forth between two fixed points. At the jumping frequency on the order of a 100 Hz and higher, and the jumping distance in the range of a few microns, the bi-concave RBC was stably trapped and stretched. The elongation of the stretched RBC was measured as a function of the beam-scanning amplitude, and the experimental results were explained qualitatively by a theoretical model.
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Full frame distilled prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.
Codex and Gemma teacher scores by category
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.000 | 0.000 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.000 | 0.000 |
| Bibliometrics | 0.000 | 0.000 |
| Science and technology studies | 0.000 | 0.000 |
| Scholarly communication | 0.000 | 0.000 |
| Open science | 0.000 | 0.000 |
| Research integrity | 0.000 | 0.000 |
| Insufficient payload (model declined to judge) | 0.000 | 0.000 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it