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A reply

2009· article· en· W1988226362 on OpenAlexaboutno aff
M. E. McBrien, G. Heyburn

Bibliographic record

VenueAnaesthesia · 2009
Typearticle
Languageen
FieldMedicine
TopicCardiac Arrest and Resuscitation
Canadian institutionsnot available
FundersAssociation of AnaesthetistsAssociation of Anaesthetists of Great Britain
KeywordsCardiorespiratory arrestMedicineCardiopulmonary resuscitationStatement (logic)Cardiorespiratory fitnessIntensive care medicineResuscitationReturn of spontaneous circulationEvent (particle physics)Medical emergencyAnesthesiaInternal medicine

Abstract

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We thank Professor Smith and Dr Poplett for their interest and encouraging comments on these guidelines. They propose simplification of the recommendations with a 2-option approach to managing patients with pre-existing Do Not Attempt Resuscitation (DNAR) decisions who are scheduled for surgery and anaesthesia. In the guidelines we used a separate section to define the rationale behind, and the implications of, a DNAR decision. The statement that ‘The term DNAR is intended to provide unambiguous instruction on one specific point – that a person should not undergo CPR in the event of cardiorespiratory arrest’ does not concur with our definitions. There are two problems with this statement. Firstly, although it is reasonable to assume that cardiopulmonary resuscitation will only ever be used following ‘spontaneous’ cardiopulmonary arrest in the out of hospital situation in which many DNAR decisions are implemented, there are in-hospital situations, including induction of anaesthesia, where cardiopulmonary resuscitation may be used when cardiopulmonary arrest has been induced by medical interventions. Cessation of spontaneous respiration, or apnoea, which frequently occurs following induction of anaesthesia, constitutes pulmonary arrest although this is not how we normally refer to it. The fact that it is iatrogenic and readily reversible, rather than a spontaneous event in the culmination of the dying process in a patient who has a terminal illness or poor quality of life, completely alters the assumptions under which the original DNAR decision was implemented. The cause of the cardiorespiratory arrest is highly relevant, and an ‘unambiguous instruction’ cannot be applied should it occur under anaesthesia. The second problem with the authors’ statement is that they argue that the DNAR decision to withhold cardiopulmonary resuscitation only becomes relevant after cardiopulmonary arrest has occurred. If this was the case, then it implies that the administration of cardiopulmonary resuscitation before cardiopulmonary arrest would not contravene a patient’s DNAR decision. This is erroneous and represents a misunderstanding of the rationale and implications of a DNAR decision. We do not believe this viewpoint should be adopted in the UK, nor should it be adopted to justify the administration of many aspects of anaesthesia, ‘which happen also to be components of CPR’ as the authors correctly state, to a patient undergoing surgery with an unmodified pre-existing DNAR decision. The purpose of publishing the guidelines was to assist doctors and patients by placing, in one document, the current ethical and legal principles involved in defining the best interests of the patient with a pre-existing DNAR decision who requires surgery, and to suggest how these may be applied to this rare but difficult situation. In doing so, we sought to protect patients from denial of their human rights as defined in the Human Rights Act 1998. We also sought to protect health professionals from retrospective accusations of assault arising from resuscitative interventions for which consent had not been granted, and from assisting euthanasia by pharmacologically inducing cardiopulmonary instability and then actively withholding cardiopulmonary resuscitation which, in other circumstances would have been indicated. To administer cardiopulmonary resuscitation to a patient who has explicitly refused such interventions in advance, even though the cardiopulmonary instability and/or arrest is pharmacologically induced, leaves an anaesthetist vulnerable to retrospective accusations of assault that may not be defensible and that may lead to criminal prosecution and referral to the General Medical Council (GMC). Under anaesthesia and surgery, the assumptions on which any pre-existing DNAR decision is made no long apply, and that is why all DNAR decisions should be reviewed in advance of surgery and anaesthesia. If the patient, proxy decision maker or doctor in charge of the patient decides that full cardiopulmonary resuscitation and its possible consequences during surgery and anaesthesia are in the patient’s best interests, then option 1 applies. If not, agreement must be made on what, if any, resuscitative interventions are acceptable, which is option 2. Agreeing to provide anaesthesia to a patient with an unmodified DNAR decision in place (option 3) would require cardiopulmonary resuscitation to be withheld, either as part of routine anaesthetic management or in the treatment of pharmacologically induced respiratory arrest. We believe that this is not in the patient’s best interests and certainly leaves the anaesthetist vulnerable to accusations of assisting euthanasia, which is currently illegal in the UK, and which may lead to criminal prosecution and GMC referral. Therefore, we believe that in most circumstances option 3 is incompatible with general anaesthesia for any type of surgery. Similar 3-option approaches have been adopted by the American Society of Anesthesiologists [1] and the Canadian Anesthesiologists’ Society [2]. We have attempted to provide guidelines that protect both patient and anaesthetist. We thank Smith and Poplett for their challenging letter, and hope this explains the rationale behind the 3-option approach recommended in the guidelines.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.775
Threshold uncertainty score0.142

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0000.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.010
GPT teacher head0.266
Teacher spread0.256 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one teacher head, not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

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Citations0
Published2009
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