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Psychological Aspects of Predictive Genetic‐Test Decisions: What Do We Know So Far?

2004· article· en· W1988411501 on OpenAlexaff
Holly Etchegary

Bibliographic record

VenueAnalyses of Social Issues and Public Policy · 2004
Typearticle
Languageen
FieldBiochemistry, Genetics and Molecular Biology
TopicBRCA gene mutations in cancer
Canadian institutionsMemorial University of Newfoundland
Fundersnot available
KeywordsPredictive testingContext (archaeology)Test (biology)PsychologyGenetic testingPredictive valueManagement scienceMedicineBiologyEngineeringGeneticsEcology

Abstract

fetched live from OpenAlex

Advances in molecular biology are facilitating the elucidation of the genetic basis of disease at an astonishing rate. Consequently, predictive genetic testing of healthy individuals may soon become a routine component of medical care. How and why is the decision to have a predictive genetic test taken? This article reviews some psychological aspects of predictive genetic‐test decisions and discusses the limitations of research to date. A notable limitation is the nontheoretic nature of much of the research. It is argued that theoretical models are needed from which hypotheses about decision making in this context can be derived and tested. Suggestions are offered for future research, and policy implications of research in this area are offered.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.013
metaresearch head score (Gemma)0.045
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Not applicable · Consensus signal: none
GenreCandidate signal: Review · Consensus signal: none
Teacher disagreement score0.013
Threshold uncertainty score0.067

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0130.045
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0010.000
Bibliometrics0.0010.002
Science and technology studies0.0020.012
Scholarly communication0.0070.007
Open science0.0010.002
Research integrity0.0040.005
Insufficient payload (model declined to judge)0.0050.001

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.038
GPT teacher head0.400
Teacher spread0.362 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designNot applicable
Domainnot available
GenreReview

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations23
Published2004
Admission routes1
Has abstractyes

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