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Record W1988617272 · doi:10.1353/hpu.2011.0156

Immune Response Due to Silica Exposure in Egyptian Phosphate Mines

2011· article· en· W1988617272 on OpenAlexfundno aff
Medhat Kalliny, Mohammad I. Bassyouni

Bibliographic record

VenueJournal of Health Care for the Poor and Underserved · 2011
Typearticle
Languageen
FieldMedicine
TopicOccupational and environmental lung diseases
Canadian institutionsnot available
FundersUniversity of TorontoCairo University
KeywordsSilicosisOccupational lung diseaseMedicineImmune systemPulmonary function testingPneumoconiosisPopulationImmunologyOccupational exposureInternal medicineEnvironmental healthPathology

Abstract

fetched live from OpenAlex

Silicosis is the most common occupational lung disease in Egypt where its prevalence rate ranges from 18.5 % to 45.8% among workers exposed to free crystalline silica dust. Despite its high prevalence, there is a lack of enforcement of exposure limits, availability and use of personal protective equipment, and occupational health education programs. These factors led the authors to study this unique working population; to the best of our knowledge, this is the first work that investigates the effect of exposure to crystalline silica on select immune response of exposed Egyptian phosphate miners. The main aims of this study were to investigate the effect of exposure to free crystalline silica on pulmonary function parameters and select immune response of exposed Egyptian phosphate miners. The study involved of three groups: 50 silica-exposed workers with radiological evidence of silicosis, 50 silica-exposed workers without evidence of silicosis, and 50 healthy unexposed subjects. There were significant differences between pulmonary function parameters in exposed groups with and without silicosis, and healthy unexposed control subjects (p<.001) and pulmonary function was significantly correlated with duration of silica exposure. Smoking had an additive effect on reduction of pulmonary function. Average values of C-reactive protein, rheumatoid factor, complement component C3, IgA, IgG, and IgM were significantly higher in the exposed group with silicosis than in the exposed group without silicosis and in healthy unexposed control subjects (p<.001).

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

How this classification was reachedexpand

Full frame machine prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.

metaresearch head score (Codex)0.000
metaresearch head score (Gemma)0.001
Version: metacan-v3-hybrid-931329e0061cValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Observational · Consensus signal: Observational
GenreCandidate signal: Empirical · Consensus signal: Empirical
Teacher disagreement score0.002
Threshold uncertainty score0.004

Distilled classifier scores by category (both heads)

CategoryCodexGemma
Metaresearch0.0000.001
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0010.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.037
GPT teacher head0.294
Teacher spread0.257 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it

Classification

machine, unvalidated

Machine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.

The models applied no category: nothing in the taxonomy fit this work.
Study designObservational
Domainnot available
GenreEmpirical

How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".

Quick stats

Citations18
Published2011
Admission routes1
Has abstractyes

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