Bibliographic record
Abstract
This paper provides a summary of recent changes to the legal, regulatory and policy environment affecting generic pharmaceutical manufacturers operating in the Canadian market. It provides a top-line overview of the Canadian pharmaceutical market in terms of generic market share by dollar value and prescriptions filled, and growth in both of those key indicators. This paper describes changes brought into force in October 2006 to regulations of Canada's Patent Act that attempt to limit ‘evergreening’ tactics employed by brand-name drug manufacturers to delay market entry of competing generic products, changes to regulations of Canada's Food and Drugs Act that provide new brand-name pharmaceutical products with eight years of data exclusivity (plus six-month paediatric exclusivity) and the response of the Canadian Generic Pharmaceutical Association (CGPA) to these regulatory changes. This paper also outlines changes to pricing and reimbursement rules for generic pharmaceutical products that are being implemented in the two largest Canadian jurisdictions of Ontario and Québec.
Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.
How this classification was reachedexpand
Full frame machine prediction
Teacher imitationNot calibrated prevalence, not ground truth. Human validation pending. The Gemma side is a direct model label for every work in the frame, read from the title-only record. The Codex side is a classifier learned from the 10,348 direct Codex labels and calibrated to design-weighted sample rates; fields without enough sample support carry no Codex call. Candidate is the union of the two sides; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels.
Distilled classifier scores by category (both heads)
| Category | Codex | Gemma |
|---|---|---|
| Metaresearch | 0.001 | 0.004 |
| Meta-epidemiology (narrow) | 0.000 | 0.000 |
| Meta-epidemiology (broad) | 0.001 | 0.001 |
| Bibliometrics | 0.002 | 0.005 |
| Science and technology studies | 0.013 | 0.006 |
| Scholarly communication | 0.010 | 0.003 |
| Open science | 0.001 | 0.003 |
| Research integrity | 0.003 | 0.003 |
| Insufficient payload (model declined to judge) | 0.015 | 0.001 |
Machine scores (provisional)
The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.
Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.
score_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from itClassification
machine, unvalidatedMachine predicted; a candidate call from one source (direct Gemma or distilled Codex), not a consensus.
How this classification was reached, model by model and score by score, is at the end of the page under "How this classification was reached".