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A Rule-Based Temporal Analysis Method for Online Health Analytics and Its Application for Real-Time Detection of Neonatal Spells

2014· article· en· W1991846816 on OpenAlex
Anirudh Thommandram, Johan Eklund, Carolyn McGregor, James E Pugh, Andrew James

Why this work is in the frame

A frame that forgets how it found something cannot be audited. These are the routes that admitted this work.

affAt least one author lists a Canadian institution in the pinned OpenAlex snapshot.

Bibliographic record

Venuenot available
Typearticle
Languageen
FieldMedicine
TopicHealthcare Technology and Patient Monitoring
Canadian institutionsHospital for Sick ChildrenUniversity of TorontoOntario Tech University
Fundersnot available
KeywordsComputer scienceRespiratory rateTimestampCardiorespiratory fitnessArtificial intelligenceHeart rateData miningReal-time computingBlood pressureMedicineInternal medicine

Abstract

fetched live from OpenAlex

Neonatal spells are cardiorespiratory events that occur in newborn infants with variable combinations of cessation of breathing, decrease in blood oxygen saturation and decrease in heart rate. A system using real-time temporal analysis of physiological data streams to accurately detect pauses in breathing and changes in heart rate and oxygen saturation for classifying neonatal spells is described. The system uses a multidimensional online health analytics environment that supports the acquisition, transmission and real-time processing of high volume, high rate data. A family of algorithms has been developed using IBM InfoSphere Streams, a scalable middleware component for analysing multiple streams of data in real-time. Respiratory pauses are identified by accurately detecting breaths and calculating time intervals between breaths. Changes in heart rate and blood oxygen saturation are identified by both threshold breaches and the detection of relative change by assessing a sliding baseline and generating alerts when values fall out of range. Events detected in individual signals are synced together based on timestamps and assessed using a classifier based on clinical rules to determine a classification of neonatal spells. The output of these algorithms has been shown, in a single use case study with 24 hours of patient data, to detect clinically significant events in heart rate, blood oxygen saturation and pauses in breathing. The accuracy for detecting these is 97.8%, 98.3% and 98.9% respectively. The accuracy for determining spells classifications is 98.9%. Future research will focus on the clinical validation of these algorithms.

Fetched live from OpenAlex and de-inverted. Abstracts are not stored in this database: the inverted indexes are 8.6 GB of the frame’s 9.3 GB of text, and the host has 13 GB free.

Full frame distilled prediction

Teacher imitation

Not calibrated prevalence, not ground truth. Human validation pending. Learned from the 10,348 direct Codex labels and 10,348 direct Gemma labels. Candidate is the union of thresholded teacher heads; consensus is their intersection. These outputs are machine_predicted_unvalidated and are not human labels or direct frontier model labels.

metaresearch head score (Codex)0.001
metaresearch head score (Gemma)0.000
Version: codex-gemma-dda1882f352aValidation status: machine_predicted_unvalidated
Candidate categoriesnone
Consensus categoriesnone
DomainCandidate signal: none · Consensus signal: none
Study designCandidate signal: Other design · Consensus signal: none
GenreCandidate signal: Empirical · Consensus signal: none
Teacher disagreement score0.910
Threshold uncertainty score0.329

Codex and Gemma teacher scores by category

CategoryCodexGemma
Metaresearch0.0010.000
Meta-epidemiology (narrow)0.0000.000
Meta-epidemiology (broad)0.0000.000
Bibliometrics0.0000.000
Science and technology studies0.0000.000
Scholarly communication0.0000.000
Open science0.0000.000
Research integrity0.0000.000
Insufficient payload (model declined to judge)0.0000.000

Machine scores (provisional)

The two teacher heads of the student model, read on this work. A score orders the frame for review; it never asserts a category, and the validation status ships verbatim with every row.

Baseline scores from an immature model (maturity gate not passed, 7 training rounds). Scores rank; they never assert a category.

Opus teacher head0.036
GPT teacher head0.380
Teacher spread0.344 · how far apart the two teachers sit on this one work
Validation statusscore_only:v0-immature-baseline · verbatim from the scoring run: score_only means the number may rank works, and no category label ships from it